Home Ethical Issues

Ethical Issues

• Research ethics
  
  
  • What are research ethics?
  • How do regulatory and ethical issues differ?
  • Are the ethical issues in repository tissue collection the same as clinical trials?
  • Are there unique ethical issues when the repository is commercial?
    
    
• Informed consent
  
  
  • Why we need informed consent
  • Is informed consent always required for tissue collection?
  • Who should conduct informed consent discussions with potential donors?
  • Is pre-surgical consent preferable to post-surgical consent?
  • Disclosures for "informed consent"
  • Why would individuals refuse?
  • Is open-ended consent ethical?
  • What is tiered consent?
  • Consent for minors
  • Opting in/opting out
  • What is group consent?
  • Consent for postmortem donation
  • Withdrawing consent
  • Redirecting remaining samples
  • Risk/benefit analysis
  • Should researchers report results to tissue donors?
  
  
  
• Privacy
  
  
  • Privacy issues and genetic information
  • Privacy mechanisms
  • De-identifying samples
  • Linked samples
  • Certificates of confidentiality
    
    
• Institutional integrity issues
  
  
  • Mission of medical center
  • Would collaboration compromise patient trust?
  • Community perceptions
  • Assessing research protocols
  • Assessing repositories
  • Tissue banking steering committees
  • What are conflicts of interest?
  • Incentives
  • Stock options
  • Appropriate incentives
  • Handling profits
  • Paying physicians